HNF1B anticorps

N° du produit ABIN2460425

L’anticorps Lapin Polyclonal anti-HNF1B a été validé pour WB et ELISA. Il convient pour détecter HNF1B dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio) et Chien.

Aperçu rapide pour HNF1B anticorps (ABIN2460425)

Antigène: HNF1B (HNF1 Homeobox B (HNF1B))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1B est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HNF1B anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCF2.

Information d'application

Indications d'application: TCF2 antibody can be used for detection of TCF2 by ELISA at 1:62500. TCF2 antibody can be used for detection of TCF2 by western blot at 0.1-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TCF2 antibody at -20 °C.

Détails sur HNF1B

Antigène: HNF1B (HNF1 Homeobox B (HNF1B))

Autre désignation: TCF2

Sujet: Hepatocyte Nuclear Factor 1-. (HNF-1., Homeoprotein LFB3, Transcription factor 2, TCF2, Variant hepatic nuclear factor ) is a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5). A third human transcript variant is believed to exist based on such a variant in the rat: however, to date such an mRNA species has not been isolated.

Poids moléculaire: 45 kDa, 61 kDa

ID gène: 6928

NCBI Accession: NP_006472

UniProt: P35680

Pathways: Hormone Transport, Stem Cell Maintenance, Tube Formation